[brazen1]

This will open PowerDVD for 2D iso's so you have menus.  Kodi now has menus also btw. 
This will open MPC-BE for UHD HDR's.
This will open Kodi internal video player for everything else.
You didn't want 3D so I didn't include anything.
You can still manually select any player using the 'play using' tab after pressing 'C' aka context menu.

Code:

<playercorefactory>
  <players>
    <player name="PowerDVD" type="ExternalPlayer" audio="false" video="true">
      <filename>C:\Program Files (x86)\CyberLink\PowerDVD17\PowerDVD.exe</filename>
      <args>"{1}" /fullscreen /close</args>
      <hidekodi>false</hidekodi>
      <hideconsole>false</hideconsole>
      <warpcursor>none</warpcursor>
    </player>
    <player name="MPC-BE" type="ExternalPlayer" audio="false" video="true">
      <filename>C:\Program Files\MPC-BE\mpcbe.exe</filename>
      <args>"{1}" /fullscreen /close</args>
      <hidekodi>false</hidekodi>
      <hideconsole>false</hideconsole>
      <warpcursor>none</warpcursor>
    </player>
  </players>
   <rules action="prepend">
    <rule filename=".*HDR10.*|.*HDR.*|.*hdr.*" player="MPC-BE"/>
    <rule filetypes="iso|bdmv|mpls|m2ts" player="PowerDVD"/>
   </rules>
 </playercorefactory>

This is the same as above but includes 3D opened with PowerDVD.  As stated above, you can still manually select a different player.

Code:

<playercorefactory>
 <players>
    <player name="PowerDVD" type="ExternalPlayer" audio="false" video="true">
      <filename>C:\Users\YOURUSERNAMEGOESHERE\AppData\Roaming\Kodi\userdata\PDVD3DISO.bat</filename>
      <playcountminimumtime>1140</playcountminimumtime>
    </player>
    <player name="MPC-BE" type="ExternalPlayer" audio="false" video="true">
      <filename>C:\Users\YOURUSERNAMEGOESHERE\AppData\Roaming\Kodi\userdata\MPCBE3DISO.bat</filename>
      <playcountminimumtime>1140</playcountminimumtime>
    </player>
 </players>
 <rules action="prepend">
    <rule filename=".*HDR10.*|.*HDR.*|.*hdr.*" player="MPC-BE"/>
    <rule filetypes="iso|bdmv|mpls|m2ts|.*3D.*|.*.3D.iso|3D.*" player="PowerDVD"/>
 </rules>
</playercorefactory>