[miappa]

Hey MrNice,
It´s difficult to know exactly what setup you have and where you came from, I don´t recognize these issues (running 2 Pi´s without issues so far, HDMI and no passtrhough).

Sound:
Passthrough? Multichannel PCM? Downmixed? Video? Music? Your settings?

First thing, see to that you start with a fresh guisettings.xml and restart XBMC. I have repeated that many times and will probably continue.
Many changes with settings, both for audio and video, and it can cause issues if you have old or invisible settings in there.
Even better is if you can start with a fresh .xbmc directory.

If that don´t help, post a debug log.

Skin:
Test again after you deleted guisettings, if it doesn´t help make a new thread and explain the issue as it might be a bug in Gotham.
I don´t use mouse myself so cannot test this.

CEC:
Libcec version was updated a while back, but this was updated in Raspbmc as well. I have included this version since November if I remember correct.
That said, do you run latest Raspbmc? There shouldn´t be any diffference if that is the case.