[Lunatixz]

@Lunatixz just a heads up that my logs for this same problem are on post #535.

I'm not seeing any standouts in your log. As I see it there are no similarities between what you are describing and @Gorodos issues.

@Gorodos needs to post a log, until then I'm going to consider many of his issues unique to his setup. I have not had issues adding custom channels, and can not replicate clicking enter custom channel group, which ends up opening the channel manager. I can also not replicate saving issues.

Make sure you start clean, close Kodi; delete all files associated with PseudoTV Live, settings.xml, library.json, channels.json, pseudotv.m3u, pseudotv.xmltv... 

I'm also planning to temporarily disable changing PseudoTV Lives paths, in-case this boils down to write permission issues. Which this plugin is not responsible for.

New logs maybe helpful so please, if you encounter an error post them... THX

If items are "Greyed out" here is the explanation found in the PseudoTV Live thread:

Settings are dim and unselectable. Some settings require content to operate (ex. Selecting TV Networks require your library have TV Content). There are also actions that can not simultaneously run while PseudoTV background tasks are performed (ie. If you wait for tasks to finish, settings will become selectable). If you experience an error message and your settings are now unselectable. Either reboot Kodi, or disable/enable PseudoTV Live to temporarily fix, and be sure to report your error with a log.

I did try an fresh install of my entire setup (removed Kodi completely and started over). 

Disappointed that my logs revealed nothing as @Gorodos description sounds exactly like mine. If I go into the setting section via the information screen I can get into the custom configuration but it never saves upon exiting. I reverted back to a previous Pseudo TV version (cant recall what at the moment, "G" perhaps?) and all is working again. It definitely started with "E".

The only issue I see with your log is the m3u its loading is malformed... looks like you have Predefined channels starting at channel 1 which isn't possible. Channels 1-999 are internally reserved for custom channels....
This should resolve itself if you start clean, maybe post another log? also be sure to NEVER manually edit any of PseudoTV Lives files and or run them through any third-party programs. You must consider the m3u/xmltv the master and any modifications either handled through PseudoTV lives UI or run independent M3U/XMLTV processing on a third-party list and use PseudoTV Lives import option to integrate that list into Pseudo...