[pkscout]

I wonder if it is possible to run a cron that selects a particular profile at a set time?

TIA

It should be.  If you're on a Linux build, there is a command line tool called kodi-send that would let you send the Runscript command mentioned in the Audio Profiles wiki entry on the Kodi page.

https://kodi.wiki/view/Add-on:Audio_Profiles

If you're on Windows or Mac, you would probably have to use curl or some other tools to send a JSON-RPC request that will run the script.  You'd need to use ExecuteAddon I think and figure out how to send the right parameters.

https://kodi.wiki/view/JSON-RPC_API/v12#...ecuteAddon

Both of these are very advanced things, and I probably can't help you more than I have.  Someone else might jump in if you try one of them and run into a challenge.